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Thioredoxin has also been shown to bind to ASK1 to inhibit its activity as a kinase [32]. This inhibition is attenuated by ROS that may lead to dimerization of thioredoxin [33]. Thioredoxin regulation from the glucocorticoid receptor via Affiliation for the DNA binding area has also been described [34] which also is motivated by ROS. A lot more lat
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